The new headquarters, based in Mansfield, is the 29th regional business for the housebuilder.
Neil Follows, managing director, Persimmon Homes, said the builder would now add to its currents homes in the region with a plan to build over 500 homes over the next few years.
He said: “We are delighted to have launched Persimmon Homes Nottingham, which represents a significant economic boost to the county.
“We have already made a number of appointments and still have positions to fill. Our focus will be on bringing in energetic, enthusiastic, local people with good knowledge of what Nottinghamshire needs and requires.
“Furthermore, there will be genuine benefits for the communities in which we work. This includes significant contributions towards education, new roads and healthcare to name but a few.”
Delivering last week’s Housing White Paper Javid addressed the stranglehold on housebuilding enjoyed by the UK’s largest 10 builders, of which Persimmon is one, adding that the UK needs a diversified housing market.