Wyles was also chairman of the Council of Mortgage Lenders for two years during 2009 and 2010.
Robert Sharpe, who became Hampshire Trust chairman in September, said: “I am truly delighted the Hampshire Trust Bank Board has secured the services of Matthew Wyles as the Bank’s next CEO following Mark’s decision to retire.
“Matthew is a practitioner well known in the retail and small business banking circles for achieving outstanding results.
“He is exactly the right person to provide the stewardship, entrepreneurial insights and the leadership to successfully steer the bank through the next stage of its development and growth.”
Wyles said: “Specialist banks are already fulfilling a key role in broadening choice for personal and business customers.
“They also play an important and growing part in making the UK economy more productive and efficient.
“Hampshire Trust Bank has already made significant progress since its acquisition by Alchemy in establishing its position as an emerging challenger – it has tremendous development potential.
“I am thrilled to have the opportunity of leading the management team to build an exceptional business on the strong foundations which are already in place.”
Hampshire Trust offers asset, property and specialist mortgage finance to individuals and small to medium enterprises (SMEs) as well as savings accounts.
Previous CEO Mark Sismey-Durrant confirmed his plans to retire in September last year, as soon as a successor could be found, after joining Hampshire Trust in 2012.