The changes will go live on 9 January and apply to purchase-only, remortgage and reward products.
This includes its two-year Premier product with an £899 fee at 60% loan to value (LTV), which will fall from 3.62% to 3.56%, while the standard equivalent product will be reduced from 3.63% to 3.57%.
The corresponding products at 75% LTV will be cut from 3.69% to 3.6% and from 3.7% to 3.61% respectively.
There is also a fee-free two-year fix at 75% LTV, which Barclays will cut from 3.9% to 3.81%.
Changes have also been made to higher-LTV products, as well as Green Home products.
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Among its remortgage-only products, the Premier two-year fix with a £999 fee at 60% LTV has been cut from 3.67% to 3.7%, while the standard option will fall from 3.71% to 3.68%.
The two-year fix at 75% LTV with a £999 fee has been reduced from 3.82% to 3.78%, while the option at 80% LTV has been cut from 4.13% to 4.09%.
Reductions have also been made to select fee-free Great Escape remortgage and Premier products.
Across its existing customer reward range, Barclays has reduced rates on selected two- and five-year fixes, either with no fee or a £999 fee, at 60% and 75% LTV.
Barclays follows HSBC, Kensington Mortgages and Gen H in lowering its rates this week.